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1例86岁女性患者因肺部感染静脉滴注头孢曲松钠2.0 g（1次/d）、阿奇霉素0.5 g （1次/d）和盐酸氨溴索30 mg（2次/d）。第4次静脉滴注阿奇霉素约30 min时，患者突然出现胸闷、憋气。心电图示Ⅲ度房室传导阻滞。立即停止药物输注，给予吸氧。1h后，患者胸闷、憋气消失。5h 后复测心电图示窦性心律。未再应用阿奇霉素，患者未再出现类似症状。“,”An 86-year-old female patient with pulmonary infection was treated with IV infusions of ceftriaxone sodium 2. 0 g once daily,azithromycin 0. 5 g once daily,and ambroxol hydrochloride 30 mg twice daily. About 30 minutes after the fourth infusion of azithromycin,the patient abruptly developed chest tightness and suffocation. Electrocardiography showed Ⅲ degree atrioventricular block. Azithromycin was stopped immediately and she was treated with oxygen inhalation. One hour later,the symptoms of chest tightness and suffocation disappeared. Five hours later,a repeat electrocardiography showed sinus rhythm. Azithromycin was not given again and the similar symptoms did not recur any more.