亚急性坏死性脑脊髓病（subacutenecrotizingencephaomyelopathy，SNE）于1951年由Leigh首次报道，又称Leigh‘s病，是一种罕见的常染色体隐性遗传性神经系统变性的疾病。主要票及婴幼儿。国内外报道较少。本文将我们所见到的3例报道如下。1临床资料倒1，男，1岁时因出现全身软 Subacute necrotizinomyomyopathy (SNE) was first reported by Leigh in 1951, also known as Leigh’s disease, a rare autosomal recessive neurodegenerative disease. The main ticket and infant. Less reports at home and abroad. This article reports the three cases we have seen below. 1 clinical data down 1, male, 1 year old because of systemic softness