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目的探讨低剂量造影剂结合低管电压在肾癌CT增强扫描中应用的可行性。方法选取医院收治的16例肾癌患者作为研究对象,随机分为对照组和观察组,每组8例。所有患者均接受腹部增强CT检查,对照组采用常规造影剂量(1.5 ml/kg)和常规管电压(120 kv),观察组采用低剂量造影剂(1.0 ml/kg)和低管电压(90 kv)。分别采集所有患者皮质期(CMP)和髓质期(NP)图像,比较2组信噪比(SNR)、对比噪声比(CNR)及肾脏实质和肿瘤组织的感兴趣区(ROI)的CT值差异。结果 2组CMP和NP图像肾脏肿瘤和肾脏皮质的CT值及CNR、SNR方面差异均无统计学意义(P>0.05)。观察组在CMP和NP图像上的辐射量均小于对照组,差异有统计学意义(P<0.05)。结论低剂量造影剂结合低管电压增强CT诊断肾癌可获得良好的图像显示,对人体伤害较小,值得临床推广应用。
Objective To investigate the feasibility of using low-dose contrast media in combination with low-voltage in CT-enhanced renal cell carcinoma. Methods Totally 16 renal cancer patients admitted to hospital were selected as study subjects and randomly divided into control group and observation group with 8 cases in each group. All patients underwent abdominal enhanced CT examination. The control group received conventional contrast (1.5 ml / kg) and conventional tube voltage (120 kv). The observation group received low dose contrast media (1.0 ml / kg) and low voltage ). The cortical phase (CMP) and medullary phase (NP) images of all patients were collected. The CT values of signal to noise ratio (SNR), contrast to noise ratio (CNR) and ROI of renal parenchyma and tumor tissues difference. Results There was no significant difference in CT value, CNR and SNR between renal tumor and renal cortex in two groups of CMP and NP images (P> 0.05). The amount of radiation of the observation group on CMP and NP images were less than that of the control group, the difference was statistically significant (P <0.05). Conclusion Low-dose contrast agent combined with low-voltage voltage-enhanced CT in the diagnosis of renal cell carcinoma can obtain a good image display, less harm to human body and worthy of clinical application.