论文部分内容阅读
代谢综合征( MS)会增加2型糖尿病、心血管疾病等的发病风险，在全球范围，发病率显著升高。阐明MS的基本病理过程对防治该病具有重要意义。慢性低水平炎症反应是导致MS的重要病理过程，而免疫球蛋白在炎症反应的发生发展中所起的作用逐渐受到关注。该文收集并评估了6项横断面研究和2项手术后随访研究，这些研究中多数结果表明MS患者血清免疫球蛋白( IgA、IgG、IgM)水平升高，提示免疫球蛋白在MS的发生、发展过程中扮演着重要的角色。“,”Metabolic syndrome ( MS) predisposes to some chronic diseases such as diabetes and cardio-vascular diseases. The prevalence of MS is increasing at alarming rates globally. The elucidation on the basic pathogenesis of MS is of great significance for the prevention and treatment. Chronic low-grade inflammation is thought to be an important pathogenesis resulting in MS, while the role of immunoglobulins in chronic inflammation is gradually paid attention to. Here we include 6 cross-sectional studies and 2 prospective stud-ies,which show the elevated levels of serum immunoglobulins (IgA,IgG,IgM) in MS patients,suggesting that the immunoglobulins may play a critical role in the initiation and development of MS.