论文部分内容阅读
自1993年12月至1996年6月，对600例胃癌、肺癌、乳腺癌、卵巢癌及恶性淋巴瘤使用康泉、枢复宁、恩丹西酮等止吐药，对化疗药物引起的呕吐疗效观察．本组第一阶段单用康泉止吐药对510例癌症患者化疗止吐率第d1、d2、d3分别为70％（357／510）、55％（280／510）、79．5％（405／510），副反应便秘8％（41／510）、头晕头痛10％（51／510）、嗜睡3％（16／510），未发现锥体外系症状及其它不良反应，未发现因呕吐反应而中断化疗患者．第二阶段用康泉、枢复宁、恩丹西酮，随机分A、B、C3组，对60例胃癌、30例乳腺癌，进行2个化疗周期止吐疗效观察，第一化疗周期d1A、B、C3组止吐有效率分别为83％（25／30）、80％（24／30）、70％（21／30）．d2有效率分别为73％（22／30）、67％（20／30）、63％（19／30）。第二化疗周期d1、d2有效率分别为77％（23／30）、70％（21／30）60％（18／30）．ABC3组头晕头痛副反应分别为6％、10％、12％，便秘分别为5％、6％、12％，嗜睡分别为3％、10％、12％，3组均未发现锥体外系及应．
From December 1993 to June 1996, antiemetic drugs such as Kangquan, Shufuning, and ondansetron were used in 600 cases of gastric cancer, lung cancer, breast cancer, ovarian cancer, and malignant lymphoma, and vomiting caused by chemotherapy drugs was used. Efficacy observation. In the first stage of this group, the antiemetic rates of dangling anticancer drugs for 510 cancer patients were d1, d2, d3, 70% (357/510), 55% (280/510), and 79.5%, respectively ( 405/510), Constipation 8% (41/510), Dizziness and headache (51/510), Drowsiness 3% (16/510). No extrapyramidal symptoms and other adverse reactions were found. No vomiting was found. Reacting while interrupting chemotherapy patients. In the second stage, Kangquan, Shufuning, and ondansetron were randomly divided into A, B, and C3 groups. 60 cases of gastric cancer and 30 cases of breast cancer were treated with 2 cycles of antiemetic efficacy. The first chemotherapy cycle was d1A. The antiemetic efficacy of group B, C3 was 83% (25/30), 80% (24/30), 70% (21/30). The d2 effective rates were 73% (22/30), 67% (20/30), and 63% (19/30), respectively. The effective rates of d1 and d2 in the second chemotherapy cycle were 77% (23/30) and 70% (21/30) 60% (18/30), respectively. The side effects of dizziness and headache in ABC3 group were 6%, 10%, and 12%, respectively, constipation was 5%, 6%, and 12%, and sleepiness was 3%, 10%, and 12%, respectively. No extrapyramidal and no extrapyramidal was found in the 3 groups. should.