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目的 探讨胃间质瘤 (GST)的组织发生病理学特点、免疫表型特征、诊断标准和治疗原则。 方法 对 65例 GST标本 ,结合临床病理特点与免疫组化进行观察。 结果 GST由梭形细胞和上皮细胞构成 ,大多数病例 vimentin、CD117、CD3 4标记阳性。 结论 与卡哈尔间质细胞有关。CD117、CD3 4是 GST的诊断性标记物。对此类肿瘤 ,手术治疗为好 ,对恶性或复发再次手术切除者 ,辅以化疗 ,可望延长病人生存期
Objective To investigate the histopathological features, immunophenotypic features, diagnostic criteria and therapeutic principles of gastric stromal tumors (GST). Methods 65 cases of GST specimens, combined with clinicopathological features and immunohistochemistry were observed. Results GST was composed of spindle cells and epithelial cells, most of which were positive for vimentin, CD117 and CD34. Conclusion is related to Cajar stromal cells. CD117, CD3 4 are diagnostic markers of GST. For such tumors, surgical treatment is good, for malignant or recurrent resection, supplemented by chemotherapy, is expected to extend the patient’s survival