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选择恰当的给药系统能明显增强药物疗效、延长作用时间及减少不良反应。近年来随着高分子化学的研究进展,眼部给药系统研究也快速发展。为了更加重视眼部给药系统的研究,笔者简述了眼部给药系统研究的进展和我国研究发展概况,并就开发我国自主知识产权的高分子聚合物材料,正确开展新型眼部给药系统的眼内药代动力学和眼毒理学研究进行了评述。
Select the appropriate drug delivery system can significantly enhance the efficacy of drugs to extend the duration of action and reduce adverse reactions. In recent years, with the progress of research on polymer chemistry, the research of ocular drug delivery system has also developed rapidly. In order to pay more attention to the research of ophthalmic drug delivery system, the author briefly described the research progress of ophthalmic drug delivery system and the general situation of research and development in China. In order to develop high molecular polymer materials with independent intellectual property rights in our country, The systematic in vivo pharmacokinetics and eye toxicology studies were reviewed.