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本文报告采用诱导化疗后手术治疗晚期(Ⅲ、Ⅳ期)喉癌43例,3年、5年生存率分别62.8％。54.2％。认为诱导化疗能提高晚期喉癌的手术切除率和生存率。1治疗方法1.1诱导化疗采用DOP方案(顺氯铵铂+长春新碱+平阳霉素)或PD方案(平阳霉素+地塞米松)。前者适用于病变相对早期、全身情况好者;后者适用于病变相对晚期、体质较差的病例。总有效66.7％～84.2％。
This article reports 43 cases of advanced stage (III, IV) laryngeal carcinoma treated with induction chemotherapy. The 3-year and 5-year survival rates were 62.8%. 54.2%. It is believed that induction chemotherapy can improve the surgical resection rate and survival rate of advanced laryngeal cancer. 1 Treatment 1.1 Induction chemotherapy using DOP regimen (cisplatin + vincristine + pingyangmycin) or PD regimen (pingyangmycin + dexamethasone). The former is applicable to patients with relatively early lesions and good general conditions; the latter is applicable to cases with relatively late lesions and poor physical conditions. The total effective 66.7% ~ 84.2%.