同种骨髓移植(Allogeneic bone marrow transplantation,Allo-MT)在临床上用于治疗再障、急性白血病、急性放射病和联合免疫缺陷等疾病,收到了较满意的疗效。它和其他脏器移植一样,也存在着不少免疫学问题。1979年3月在慕尼黑召开的国际座谈会上,专门讨论了骨髓移植中的免疫生物学问题。Thomas(1977)在总结100例急性白血病Allo-BMT的经验时指出,四大死因之一是移植物抗宿主病(Graft versus host disease。GV Allogeneic bone marrow transplantation (Allogeneic bone marrow transplantation, Allo-MT) in the clinical treatment of aplastic anemia, acute leukemia, acute radiation sickness and combined immunodeficiency and other diseases, received more satisfactory results. It and other organ transplant, there are also many immunological problems. In March 1979 in Munich, held an international symposium, devoted to immunobiology in bone marrow transplantation. In summarizing the experience of 100 cases of acute leukemia Allo-BMT, Thomas (1977) pointed out that one of the four major causes of death was Graft versus host disease