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应用OKT抗人T细胞单克隆抗体,Lemn等发现在急、慢性乙型肝炎患者的外周血中,T细胞总数减少,T辅助亚群与T杀伤-抑制亚群的比例(T4/T8)降低,提示调节性T细胞数目或功能紊乱对乙型肝炎的发生、消退及转为HBsAg慢性携带状态有重要意义,但有关HBsAg无症状携带者外周血T细胞数目的报道很少,以往应用E花环检测的结果不一致。为了探讨HBsAg在携带者体内长期存在而又不引起明
Using OKT anti-human T cell monoclonal antibody, Lemn et al found that in the peripheral blood of patients with acute and chronic hepatitis B, the total number of T cells decreased, and the ratio of T helper subgroup to T killer subgroup (T4 / T8) decreased , Suggesting that the number of regulatory T cells or dysfunction of hepatitis B occurs, regression and conversion to chronic HBsAg status is important, but the number of asymptomatic carriers of HBsAg T cells rarely reported in the past the use of E-rings The test results are inconsistent. In order to investigate the long-term presence of HBsAg in carriers without causing a problem