论文部分内容阅读
儿童急性巨核细胞白血病(AMKL)的骨髓移植(BMT)治疗,至今文献中仅见6例报道。作者报告了6例儿童 AMKL 及1例急性骨髓纤维化的临床、血液学、染色体核型及 BMT 治疗结果。本组病例均经形态学、细胞化学、免疫表型和/或血小板过氧化酶活性检查确定。FAB 分类为AML-M_7。6例接受异基因 BMT(allo-BMT),1例接受自身 BMT(ABMT)及 allo-BMT。年龄最小10个月,最大11岁。从诊断到移植时间为6～12个月。所
In childhood bone marrow transplantation (BMT) treatment of acute megakaryocytic leukemia (AMKL), only 6 cases have been reported in the literature to date. The authors reported clinical, hematologic, karyotypic and BMT treatment outcomes in 6 children with AMKL and 1 with acute myelofibrosis. All cases were confirmed by morphological, cytochemical, immunophenotypic, and/or platelet peroxidase activity tests. FAB was classified as AML-M_7. Six patients received allogeneic BMT (allo-BMT) and one patient received its own BMT (ABMT) and allo-BMT. The minimum age is 10 months and the maximum is 11 years old. The time from diagnosis to transplantation is 6 to 12 months. By