紫杉醇是新一类抗微管药物，具有广泛的抗肿瘤活性，尤其在卵巢癌、乳腺癌有较好的疗效。在早期的临床使用过程中，曾发生严重的过敏反应，表现为呼吸困难、低血压、心动过速、尊麻疹、皮肤潮红等甚至致病人死亡，使临床研究工作曾一度中断［1］。以后因应用较严格的抗过敏方案 Paclitaxel is a new class of anti-microtubule drugs, with a wide range of anti-tumor activity, especially in ovarian cancer, breast cancer has a good effect. In the early stages of clinical use, severe allergic reactions have occurred, manifested as dyspnea, hypotension, tachycardia, hives, cutaneous flushing, and even death of patients, leaving clinical research work interrupted for a time [1]. Later due to the application of more stringent anti-allergic programs