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目的 :探讨肺粘膜相关型淋巴瘤和肺炎性假瘤的病理特征及相互关系。方法 :对 9例肺粘膜相关型淋巴瘤和 6例肺炎性假瘤进行临床病理及免疫组化研究。结果 :男性多见 ,平均年龄 5 8岁 ,干咳、胸闷、胸痛为主要症状。病理形态 :肺粘膜相关型淋巴瘤 9例 ,细胞类型 ,CCL细胞性 6例、小淋巴细胞性 2例 ,淋巴浆细胞性 1例。肺炎性假瘤 6例。免疫组化证实 ,肺粘膜相关型淋巴瘤 9例LCA+ 、L2 6 + 、IgM、κ或λ呈单克隆性 ,6例炎性假瘤显示多克隆性。 结论 :两者临床鉴别困难 ,病理诊断须依靠免疫组化才能鉴别 ,两者均应以手术治疗为主。
Objective : To investigate the pathological features and relationship between pulmonary mucosa-associated lymphoma and pneumonia pseudotumor. Methods: Clinical pathology and immunohistochemical study were performed on 9 cases of pulmonary mucosa-associated lymphoma and 6 cases of pneumonia pseudotumor. Results: Men were more common with an average age of 5 8 years. Dry cough, chest tightness and chest pain were the main symptoms. Pathological morphology: 9 cases of lung mucosa-associated lymphoma, cell type, 6 cases of CCL cell, 2 cases of small lymphocyte, 1 case of lymphoplasmacytic. Pneumonia pseudotumor in 6 cases. Immunohistochemistry confirmed that 9 cases of LMA+, L2 6+, IgM, kappa, or lambda were of monoclonality, and 6 cases of inflammatory pseudotumor showed polyclonality. Conclusion: The clinical differentiation between the two is difficult, pathological diagnosis must rely on immunohistochemistry to identify, both should be based on surgical treatment.