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目的:探讨药物经济学理论在临床合理用药中的应用价值。方法:选择2013年1月~2015年12月在台州市博爱医院消化科门诊接受药物治疗的202例消化性溃疡并幽门螺旋菌感染患者,按照治疗方案的不同分为甲组、乙组、丙组,比较三种治疗方案的治疗效果、C/E、△C/△E。结果:乙组HP根除率、溃疡愈合率最高,其次为甲组,其中丙组最低,甲组、乙组HP根除率、溃疡愈合率与丙组比较,差异显著(P<0.05);而甲组与乙组比较差异无统计学意义(P>0.05)。三种方案在成本/效果比较中,丙组最低,甲组次之,乙组最高;因丙组方案成本最低,治疗效果较差,将其作为增量成本效果比(△C/△E)的参照,甲组方案每升高一个百分单位所需成本为乙组方案的一半左右。结论:药物经济学理论在临床合理用药中能为患者选择更佳的治疗方案,降低治疗成本,减少治疗时间,使用药有效、经济、安全、适用。
Objective: To explore the application value of pharmacoeconomic theory in clinical rational drug use. Methods: From January 2013 to December 2015, 202 patients with peptic ulcer and Helicobacter pylori infection who received drug treatment in Department of Gastroenterology, Pok Oi Hospital of Taizhou City were selected and divided into groups A, B, C Group, to compare the therapeutic effect of three treatment options, C / E, △ C / △ E. Results: In group B, the eradication rate of HP and the rate of ulcer healing were the highest, followed by group A, the lowest in group C, the eradication rate in group A and group B, and the healing rate in ulcer in group B (P <0.05) There was no significant difference between group B and group B (P> 0.05). Among the three schemes, the cost / benefit comparison is the lowest in group C, followed by group A, and the highest in group B. The lowest cost and the less effective treatment result in group C as the incremental cost-effectiveness ratio (△ C / △ E) , The cost per unit of increase in Unit A costs about half of that in Unit B. Conclusion: The theory of pharmacoeconomics can choose a better treatment plan for patients in clinical rational medicine, reduce the treatment cost, reduce the treatment time, and make the medicine effective, economical, safe and applicable.