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目的观察参芪扶正注射液对乳腺癌化疗患者心脏毒性及免疫功能等方面的作用和影响。方法将60例乳腺癌患者随机分成治疗组和对照组,治疗组在对照组用药基础上与化疗同步给予参芪扶正注射液,观察2组化疗前后心功能及免疫功能变化。结果治疗组治疗后NK细胞与治疗前相比升高(P<0.05),且治疗组的心肌损伤程度降低,异常心电图的发生率小于对照组。结论参芪扶正注射液辅助化疗治疗乳腺癌,能提高患者机体的免疫功能,并降低患者心脏毒性。
Objective To observe the effects and the effects of Shenqi Fuzheng Injection on cardiotoxicity and immune function in patients with breast cancer undergoing chemotherapy. Methods Sixty patients with breast cancer were randomly divided into treatment group and control group. The treatment group was given Shenqi Fuzheng injection simultaneously with chemotherapy on the basis of the control group, and the changes of cardiac function and immune function were observed before and after chemotherapy. Results The NK cells in treatment group were significantly higher than those before treatment (P <0.05), and the degree of myocardial injury in treatment group decreased. The incidence of abnormal ECG was lower than that in control group. Conclusion Shenqi Fuzheng injection adjuvant chemotherapy in the treatment of breast cancer can improve the patient’s immune function and reduce the patient’s cardiotoxicity.