为了对青蒿素的合成提供有用的讯息,我们在经过改进后的日本分光株式社(JASCO)的ORD/UV-5型自动记录旋光色散计上,测定了图1所示的青蒿素合成过程中8个内酯类的产物的旋光色散曲线(图2～4)并结合Dreiding模型和内酯的扇形规则、手性规则和C_β规则以及羰基的八区律确定了它们的A、B、C环的稠合方式及有关基团的配置(图2～4),并进行了讨论。 In order to provide useful information on the synthesis of artemisinin, we measured the artemisinin synthesis shown in Figure 1 on an improved ORD / UV-5 automated recording polarimeter by JASCO The optical rotation dispersion curves of the eight lactones (Figures 2-4) and their relation to the fancy rule, the chirality rule and the C_β rule of carbonyl compounds and the eight-zone law of carbonyls were used to determine their A, B, C ring condensation and related group configuration (Figure 2 ~ 4), and were discussed.