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目的探讨缺血性脑卒中和踝臂指数(ankle-brachial index,ABI)的关系。方法 2008年10月至2010年10月就诊的414例急性缺血性脑卒中患者为病例组,92例急性脑出血患者为对照组,通过简化方法测量其踝臂指数,同时收集相关资料。运用SPSS 14.0软件建立数据库,并进行统计学处理。结果病例组ABI<0.9有33例,对照组0例,病例组ABI中值是1.030 0,四分位距0.16;对照组ABI中值是1.156 5,四分位距0.14。单因素Logistic回归分析显示,缺血性脑卒中与ABI<0.9(OR=3.364,CI:2.607～4.339,P<0.001)、年龄(OR=3.218,CI:2.512～4.123,P<0.001)、高血压(OR=20.918,CI:11.747～37.249,P<0.001)、糖尿病(OR=4.340,CI:1.948～9.669,P<0.001)、心脏病(OR=2.539,CI:1.408～4.579,P=0.002)、肥胖(OR=4.324,CI:1.536～12.174,P=0.006)、酗酒(OR=0.498,CI:0.255～0.973,P=0.041)相关。多因素logistic回归分析显示,缺血性脑卒中与高血压(OR=11.332,CI:5.941～21.613,P<0.001)、年龄(OR=2.519,CI:1.852～3.425,P<0.001)、ABI<0.9(OR=0.020,CI:0.002～0.186,P<0.001)、肥胖(P=0.007,OR=5.967,CI:1.641～21.692)、糖尿病(OR=2.515,CI:0.984～6.431,P=0.054)相关。结论简化方法测得ABI<0.9与缺血性脑卒中相关,ABI<0.9、年龄、高血压、肥胖和糖尿病是缺血性脑卒中的独立危险因素。
Objective To investigate the relationship between ischemic stroke and ankle-brachial index (ABI). Methods 414 patients with acute ischemic stroke admitted to our hospital from October 2008 to October 2010 were selected as the case group and 92 patients with acute cerebral hemorrhage as the control group. The ankle-brachial index was measured by a simplified method and the relevant data were collected. The use of SPSS 14.0 software to establish a database, and statistical processing. Results In the case group, there were 33 cases with ABI <0.9 and 0 cases with control group. The median ABI was 1.030 0 and the interquartile range was 0.16. The median ABI of the control group was 1.156 5 and the interquartile range was 0.14. Univariate Logistic regression analysis showed that there was no significant difference between ischemic stroke and ABI <0.9 (OR = 3.364, CI: 2.607-4.393, P <0.001) (OR = 20.918, CI: 11.747-37.249, P <0.001), diabetes (OR = 4.340, CI: 1.948-9.669, P <0.001) and heart disease (OR = 2.539, CI: 1.408-4.579, P = 0.002 ), Obesity (OR = 4.324, CI: 1.536-12.124, P = 0.006), alcohol abuse (OR = 0.498, CI: 0.255-0.973, P = 0.041). Multivariate logistic regression analysis showed that there were significant differences in the incidence of ischemic stroke between hypertension and stroke (OR = 11.332, CI: 5.941-21.613, P <0.001) (OR = 2.515, CI: 0.984 ~ 6.431, P = 0.054) were significantly higher than those in control group (OR = 0.020, CI: 0.002-0.186, P <0.001) Related. Conclusions ABI <0.9 was associated with ischemic stroke with ABI <0.9, and age, hypertension, obesity and diabetes mellitus were independent risk factors for ischemic stroke.