Taking the gold ore deposit concentrating area of Jiaodong area in Shandong, China for an example, based on geological analysis, and applying Gresens' equation, Grant's isocon diagram and O'hara microelement calculation method, a thorough study on shear alteration, mass transfer and gold mineralization was carried out. The authors also made mathematic simulation and geochemical analysis. The work reveals temporal-spatial changing regularities of temperature field and velocity field of fluids, and also reveals fluid transport-chemical reaction coupling metallogenic dynamics of the Jiaojia gold ore concentrating area. During shear-alteration process of the Jiaodong gold ore concentrating area, all kinds of components transferred with different amounts, fluid-rock ratio was rather high and volume strain was of dilation type. Fast flow of ore-forming fluid favors the occurrence of mixed fluid. Shear-fractured zones are places where there was strong transportationreaction coupling mineralization. Ore bodies were located in dilation space of shear structure where there was the greatest fluid flux. After the emplacement of the rock body, a convex heat field was formed around the rock body. It is one of the main metallogenic forces. The major reason for mineralization is the mobilization, migration and enrichment of ore-forming elements induced by shear compressive-extensional tectonism. Inclusion gold dominant Iow-grade ores were formed in the early ore-forming stage, while high-grade ores, which contained fissure gold and polymetallic veinlets, were formed in late ore-forming stage.