论文部分内容阅读
对507例中国人载脂蛋白E(apoE)表型及其等位基因频率进行分析,并比较东、西方民族间的异同。结果表明,中国人群apoE3/3表型分布及其等位基因ε3的频率与东方民族(日本)基本一致,但明显高于西方人群。中国人群的apoE3/4表型分布频率不仅低于西方人群,而且也低于东方其它民族。其它表型的分布频率在人群间无明显差异.可以认为apoE的表型分布及其等位基因频率在中国人群与西方人群之间存在着种族差异性。
The phenotype and allele frequencies of apoE in 507 Chinese were analyzed, and the similarities and differences between east and west peoples were compared. The results showed that the phenotype distribution of apoE3 / 3 and the frequency of its allele ε3 in Chinese population were basically the same as those in the East (Japan), but significantly higher than those in the West. The frequency of apoE3 / 4 phenotype distribution in Chinese population is not only lower than that of Western populations, but also lower than that of other ethnic groups in the East. There was no significant difference in the distribution frequency of other phenotypes between populations, and it is believed that the phenotypic distribution of apoE and its allele frequency may have racial differences between Chinese and Western populations.