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用放射免疫和perter－silber成色反应方法分别测定了19名口腔粘膜糜烂型扁平苔藓患者（女11人、男8人）经一疗程（10次）病损区粘膜下糖皮质激素注射治疗前后其血浆中皮质醇和24小时尿17-羟类固醇（17-OHCS）的含量。结果显示：经激素局部注射治疗后，患者血浆中的皮质醇水平及尿17－OHCS的含量与治疗前相比均无明显差异（P＜0．05）。研究结果说明：局部激素注射治疗对糜烂型OLP患者的肾上院皮质功能未产生明显的影响，患者的肾上院皮质分泌功能未受到抑制，提示该治疗方法是比较安全、有效和值得在临床上选用的．
Nineteen patients with oral mucosal erosive lichen planus (11 females and 8 males) were measured by radioimmunoassay and perter-silber colorimetry respectively before and after subcutaneous subcutaneous glucocorticoid injection for one course of treatment (10 times) Plasma cortisol and 24-hour urinary 17-hydroxysteroid (17-OHCS) content. The results showed that there was no significant difference in plasma cortisol level and urinary 17-OHCS level between the two groups (P <0.05). The results show that: local hormone injection treatment of erosive OLP in patients with superior renal cortical function did not have a significant effect, the patient's superior cortical secretion was not inhibited, suggesting that the treatment is relatively safe, effective and is worth the clinical selection of.