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目的:探讨巨大性甲状腺肿性Graves甲亢患者的临床治疗过程中,应用131Ⅰ进行治疗的临床效果。方法:选取广东药学院附属第一医院2009年6月-2014年6月收治的120例巨大性甲状腺肿性Graves甲亢患者作为研究对象,随机分为观察组与对照组各60例。对照组给予常规治疗,观察组以常规治疗为基础,给予131Ⅰ治疗,对比两组患者的临床治疗效果。结果:观察组治疗总有效率为96.7%,对照组治疗总有效率为73.3%,治疗效果明显低于观察组(P<0.05),具有统计学意义。结论:巨大性甲状腺肿性Graves甲亢患者的治疗过程中,应用131Ⅰ进行治疗,具有较好效果,可有效提高患者的治疗总有效率。
Objective: To investigate the clinical effect of 131 Ⅰ treatment in the clinical treatment of patients with giant goiter. Methods: One hundred and twenty patients with giant goitest hyperthyroidism who were admitted to the First Affiliated Hospital of Guangdong University of Pharmacy from June 2009 to June 2014 were selected as study subjects and randomly divided into observation group and control group with 60 cases each. The control group was given routine treatment. The observation group was given 131 Ⅰ treatment on the basis of routine treatment, and the clinical treatment effect was compared between the two groups. Results: The total effective rate of observation group was 96.7%, while that of control group was 73.3%. The therapeutic effect was significantly lower than that of observation group (P <0.05), with statistical significance. Conclusion: The treatment of giant goiter with Graves hyperthyroidism in patients with 131 Ⅰ treatment, with good results, which can effectively improve the patient’s total effective rate of treatment.