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目的:本实验在以STZ诱导并以高糖灌胃加重病变的糖尿病大鼠模型上观察血清、红细胞内Na~+、K~+、Ca~(2+)离子浓度的变化,并观察了腹腔注射丹参注射液对以上指标的影响。结果:与正常大鼠相比,糖尿病大鼠红细胞内Na~+、Ca~(2+)浓度明显升高,K~+浓度明显降低(P<0.01);血清中Na~+、ca~(2+)浓度降低,K~+浓度升高(P<0.01)。结论:丹参注射液能显著改善红细胞内外Na~+、K~+、Ca~(2+)的紊乱(P<0.05或P<0.01),但对血糖无影响。
OBJECTIVE: To observe the changes of Na ~ +, K ~ + and Ca ~ (2+) in serum and erythrocytes in diabetic rats induced by STZ and hyperglycemia, Effect of injection of Salvia injection on the above indexes. Results: Compared with normal rats, Na + and Ca2 + in erythrocytes were significantly increased and K + concentration was significantly decreased in diabetic rats (P <0.01) 2+) decreased and K + concentration increased (P <0.01). Conclusion: Salvia miltiorrhiza injection can significantly improve the disorder of Na ~ +, K ~ +, Ca ~ (2+) in erythrocytes inside and outside (P <0.05 or P <0.01), but has no effect on blood glucose.