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已报道有20多例服用加替沙星与低血糖或高血糖症有关。本文比较了服用加替沙星和其他喹诺酮类药物引起体内葡萄糖平衡异常(GHA)不良反应(AERs)的发生率。作者从美国FDA获得1997年11月～2003年9月期间环丙沙星、加替沙星、左氧氟沙星和莫西沙星特发的不良反应报告,剔除重叠和国外的病例,用编制特定的术语来确定GHA AERs,并统计GHA AER发生率,以发生不良反应的总数或零售处方药总数作为标准计算后进行评价。
More than 20 cases of gatifloxacin have been reported to be associated with hypoglycemia or hyperglycemia. This article compares the incidence of adverse effects of glucose (GHA) in adults (GERs) on gatifloxacin and other quinolones. The authors received reports of the adverse reactions of ciprofloxacin, gatifloxacin, levofloxacin and moxifloxacin during the period from November 1997 to September 2003 from the US FDA, excluding overlapping and foreign cases, using specific terms Determine the GHA AERs, and statistics GHA AER incidence, the total number of adverse reactions or retail total number of prescription drugs as a standard calculation and evaluation.