目的:对吸吮无营养安慰剂、经口给予30%蔗糖溶液、局部应用Emla(?)和将任何二者联合应用在早产儿EPO皮下注射过程中的镇痛效果进行对比。方法:这是一项随机的、前瞻性的研究,共历时5个月。研究对象为出生时胎龄不足33周,已经生后8 d及需要注射EPO (每周皮下注射3次,连续6周)的新生儿。所有研究对象被随机分为4组:吸吮无营养安慰剂组(T),经口给予0.2-0.5 ml 30%的蔗糖溶液并吸吮无营养安慰剂组 PURPOSE: To compare the analgesic effect of sucking unexposed placebo, 30% sucrose solution orally, topical application of Emla (?), And any combination of both in the EPO subcutaneous injection of preterm infants. Methods: This is a randomized, prospective study lasting 5 months. The subjects were neonates with gestational age less than 33 weeks, 8 days after birth, and EPO (3 times a week for 6 weeks). All subjects were randomized into 4 groups: sucking non-nutritive placebo (T), orally administering 0.2-0.5 ml of 30% sucrose solution and sucking non-nutritive placebo