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新型冠状病毒(2019-nCoV)、严重急性呼吸综合征(severe acute respiratory syndrome coronavirus, SARS-CoV)及中东呼吸综合征(Middle East respiratory syndrome coronavirus, MERS-CoV)对全球公共卫生安全造成严重威胁。虽然冠状病毒(Coronavirus, CoV)的主要感染途径为呼吸道感染,既往呼吸道病毒的研究和目前2019-nCoV相关报道表明该类病毒导致输血传播性疾病(transfusion transmitted disease, TTD)的可能性较小,但可在患者血浆中检测到病毒RNA,因此,尚无证据完全排除其通过输血传播的可能性。本文结合CoV特征、经血液传播途径的理论研究及数据分析,对CoV与TTD的相关性进行探讨,总结了采供血机构针对新冠肺炎(COVID-19)疫情发展现状应采取的防控措施,为保障COVID-19疫情防控期间临床用血安全提供了2019-nCoV的输血传播风险分析和应对策略。“,”Novel coronavirus (2019-nCoV), severe acute respiratory syndrome coronavirus(SARS-CoV), and Middle East respiratory syndrome coronavirus(MERS-CoV) had posed a serious threat to global public health security. Although the main route of infection of the coronavirus is respiratory infection and it is less likely to cause transfusion transmitted disease (TTD), there was no evidence to completely rule out the possibility of transmission through blood transfusion because of the presence of the virus RNA in the plasma of patients. Based on the characteristics of the coronavirus and theoretical research and data analysis of the route of blood transmission, this paper discusses the relationship between coronavirus and TTD, summarizes the prevention and control measures that should be taken by blood collection and supply institutions, and provides the risk analysis and coping strategies of blood transfusion transmission of 2019-nCoV to ensure the blood safety during the COVID-19 epidemic situation.