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目的 探讨心舒口服液对心脏功能的药理作用机理。方法 采用麻醉犬冠脉血流量 ,左室作功能力和心肌耗氧量等指标的变化 ,研究心舒口服液对心肌作用机理。结果 心舒口服液可以明显增加冠脉血流量 ,改善心肌收缩功能。结论 心舒口服液对心脏功能有明显调节和改善作用 ,为进一步临床研究提供实验依据。
Objective To investigate the pharmacological mechanism of Xinshu oral liquid on heart function. Methods The changes of myocardial blood flow, left ventricular function and myocardial oxygen consumption in anesthetized dogs were used to study the mechanism of Xinshu oral solution on myocardial function. Results Xinshu oral liquid can significantly increase coronary blood flow and improve myocardial contractile function. Conclusion Xinshu oral liquid has obvious regulation and improvement effect on heart function, and provides experimental basis for further clinical research.