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目的推广和应用在肾综合征出血热(HFRS)高发区实施以疫苗接种为主的新防控对策成果,为指导我区HFRS的防控,制定预防策略提供科学依据。方法在呼伦贝尔市已完成HFRS疫苗突击接种的四个旗,分别对每年新进入高危年龄的人群(发病率100/10万的乡镇,10岁人群;发病率高于50/10万低于100/10万的乡镇16岁人群)和(发病率高于10/10万低于50/10万的乡镇,20~59岁男性人群),实施杭州天元公司出品的双价HFRS疫苗接种,免疫接种率在80%以上。结果通过3年(2005~2007年)项目实施,重点地区HFRS发病率和死亡率分较接种前下降40.41%和76.47%。结论在HFRS高发地区实施大人群突击性免疫接种后,每年只免疫新进入高危年龄段的人群,可以巩固突击免疫的成果,使发病持续下降。
Objective To popularize and apply the new prevention and control measures of vaccination in the high incidence area of hemorrhagic fever with renal syndrome (HFRS), and to provide a scientific basis for the prevention and control of HFRS in our area and the formulation of prevention strategies. Methods In Hulunbeir city, four flags of surprise vaccination with HFRS vaccine have been completed, and each of the newly entered high-risk age groups (townships and townships with a prevalence rate of 100 / 100,000 and 10-year-olds; incidence higher than 50 / 100,000 / 100 / 100000 township 16 years old) and (incidence more than 10/10 million less than 50/10 million townships, 20 to 59-year-old male population), the implementation of Hangzhou Tianyuan company produced double-price HFRS vaccination, immunization rates Above 80%. Results The project was implemented in three years (from 2005 to 2007). The incidence and mortality of HFRS in key areas dropped by 40.41% and 76.47% respectively compared with that before inoculation. Conclusions After the large-scale surprise immunization in high-risk areas of HFRS, only immunization of new-age high-risk groups annually can consolidate the results of the blitzkrieg immunization and keep the incidence falling.