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在活体中标记红细胞需要三个条件:(1)亚锡(Sn)离子;(2)血浆蛋白;(3)高锝酸钠(Na~(99)mTcO4)。Tc在血液中和血红蛋白结合需要一定时间,在未结合前就有部分进入细胞外液。这样的成像往往本底很高,而且Tc在肝和胃中浓度很高,但如使红细胞和Tc在体外注射器内标记,显像结果要好得多,本底较低,且图像清晰。标记后的一个问题是准直器的选择。离准直器越近的物体影像越清楚。准直器有高分辨力、通用和高敏感度三种。用气球模拟心脏,用三种准直器成像结果看来,通用准直器优于高分辨力和高敏感度的准直器。但若多次重复试验,则高分辨力准直器引起的变异最小,通用的也可以,高敏感度的准直器变异最大。
Three conditions are required to label erythrocytes in a living body: (1) stannous (Sn) ions; (2) plasma proteins; (3) sodium pertechnetate (Na ~ (99) mTcO4). It takes some time for Tc to bind to hemoglobin in the blood, and some of it enters the extracellular fluid before it is bound. Such imaging often has a high background, and Tc is highly concentrated in the liver and stomach. However, if red blood cells and Tc are labeled in an in vitro syringe, the imaging results are much better, the background is lower, and the image is clear. One of the problems after marking is the choice of collimator. The closer the object to the collimator, the clearer the image. Collimator with high resolution, universal and high sensitivity of three. With balloons simulating the heart, with three collimator images, the common collimator appears to outperform the high-resolution and high-sensitivity collimators. However, if repeated experiments, the high-resolution collimators caused the smallest variation, universal, high-sensitivity collimator variation maximum.