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1例88岁男性患者因心房颤动急性加重就诊。患者既往有支气管哮喘病史,但来诊时无哮喘发作表现。给予患者胺碘酮150 mg溶于5%葡萄糖注射液10 ml缓慢静脉推注(1 ml/min),用药约6 min(胺碘酮剂量约90 mg)时患者突然出现呼吸骤停伴全身发绀、意识丧失、双肺无呼吸音。立即停用胺碘酮,予辅助呼吸和氧疗。呼吸停止2 min后患者意识及呼吸逐渐恢复,但出现明显呼气性呼吸困难,双肺满布哮鸣音。加用甲泼尼龙和多索茶碱。8 min后患者神志逐渐转清,肺部哮鸣音消失,心室率稳定于70～80次/min。25 min后患者憋喘、心悸症状消失。
A 88-year-old male patient presented with an acute exacerbation of atrial fibrillation. The patient had a history of bronchial asthma, but no asthma attack at presentation. Patients were given amiodarone 150 mg dissolved in 5% dextrose in 10 ml slow intravenous injection (1 ml / min) and the patient developed sudden respiratory arrest with systemic cyanosis at about 6 min (amiodarone dose of about 90 mg) , Loss of consciousness, no lung breath sounds. Immediate withdrawal of amiodarone, to aid breathing and oxygen therapy. Patient consciousness and respiration gradually recovered after 2 min of respiration, but significant expiratory dyspnea was noted and both lungs covered with wheeze. Add methylprednisolone and doxofylline. After 8 min, the consciousness of the patient gradually cleared, the wheeze of the lung disappeared, and the ventricular rate stabilized at 70 to 80 beats / min. After 25 min, the patient was breathless and symptoms of palpitations disappeared.