论文部分内容阅读
文献报道,从骆驼蓬(Peganum harmala)种子中首次提取分离的骆驼蓬碱具有兴奋中枢神经系统作用。已知骆驼蓬的种子含有多种生物碱,其中骆驼蓬碱和去氢骆驼蓬碱还是较强的致幻剂。离体主动脉条实验显示骆驼蓬碱在未达到自身直接作用的剂量时,对苯福林和肾上腺素引起的收缩具有促进作
It was reported in the literature that the first extraction and isolation of harmaline from Peganum harmala seeds has a central nervous system effect. It is known that seeds of Peganum harmonii contain a variety of alkaloids, of which harmapine and harmonine are also potent hallucinogens. In vitro aortic bar experiments showed that harmonine has a positive effect on phenylephrine and epinephrine-induced contractions when it does not reach its own direct-acting dose.