NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid l

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：ashwingangel

【摘要】

：

Acute myeloid leukemia(AML) is an aggressive hematological malignancy, and the mechanism underlying immune system involvement in leukemia development is unclear

【作者】

：

WANG YaJie CHEN Chen DONG Fang

【机构】

：

StateKeyLaboratoryofExperimentalHematology,CenterforStemCellMedicine,DepartmentofStemCellandRegenera

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2015年12期

【关键词】

：

白血病细胞 NK细胞早期阶段 CD226 免疫系统相互作用急性恶性血液病 acute myeloid leukemia natural killer c

【基金项目】

：

We thank Dr. Yayi Hou from Nanjing University for proofreading. We are also grateful to our lab members and collaborators for their assistance with the experiments and in the preparation of the manusc

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Acute myeloid leukemia(AML) is an aggressive hematological malignancy, and the mechanism underlying immune system involvement in leukemia development is unclear. In the present study, we utilized a myeloid/lymphoid or mixed-lineage leukemia; translocated

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NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid l

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