目的　为了观察抗癫痫药物的疗效与血浓度的关系。方法　用抑制免疫速率散射比浊法测定了5 5例癫痫病人的苯妥因钠、鲁米那、卡马西平的药物血浓度 ,男 36例 ,女 19例 ,癫痫大发作 40例 ,颞叶癫痫 15例。结果　单用药物的血浆浓度有效率达 73.3% ,合并用药有效率达 6 3.9%。结论　该方法快速、敏感、简便对癫痫的治疗提供了可靠的实验室数据 ,本研究提示在癫痫治疗过程中进行治疗药物监测是非常必要的。 Objective To observe the relationship between antiepileptic drug efficacy and blood concentration. Methods The blood concentration of phenytoin sodium, luminal and carbamazepine in 55 epileptic patients was determined by the method of immunostaining nephelometry. Thirty-six males, 19 females, 40 epileptic seizures, Epilepsy in 15 cases. Results The plasma concentration of single drug was 73.3% and the effective rate of drug combination was 6 3.9%. Conclusion The method is rapid, sensitive and simple and provides reliable laboratory data for the treatment of epilepsy. This study suggests that it is necessary to monitor the therapeutic drugs during the treatment of epilepsy.