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本文旨在研究比较早晨与夜间每日一次服法莫替丁40 mg治疗胃溃疡的疗效。病人与方法:经胃镜证实有活动性胃溃疡179例患者,随机分为两个治疗组:早晨组88例(男58例,女30例,年龄49.9±12.8岁)上午8时口服法莫替丁40 mg;夜间组91例(男69例,女22例,年龄52.2±14.4岁)下午10时口服同样剂量。溃疡直径≤5mm及拒绝内镜复查者剔除,实际列入统计的患者早晨组81例和夜间组83例。在治疗前24h内给患者作胃镜检查,间隔4周胃镜复查直到证实溃疡愈合,溃疡在达到完全上皮化才算治愈。溃疡按Sakita内镜分期分类法分期。治疗时记录患者各种症状。总的症状规定
This article aims to study the efficacy of 40 mg famotidine once daily in the morning and evening to treat gastric ulcer. Patients and Methods: 179 patients with active gastric ulcer confirmed by endoscopy were randomly divided into two treatment groups: 88 patients (58 males and 30 females, aged 49.9 ± 12.8 years) in the morning group were given oral famotidine Ding 40 mg; night group of 91 patients (69 males and 22 females, aged 52.2 ± 14.4 years) at 10 o’clock the same dose. Ulcer diameter ≤ 5mm and reject endoscopic review were excluded, the actual inclusion of patients in the morning group of 81 patients and night group of 83 patients. Gastroscopy was performed on the patients within 24 hours before treatment, and gastroscopy was performed 4 weeks apart to confirm ulcer healing. The ulcer was completely cured before reaching complete epithelialization. Stages according to Sakita endoscopic staging classification. Treatment of patients with various symptoms recorded. The general symptoms