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目的探讨甲状腺微小癌的临床病理特征。方法对北京大学人民医院病理科2007-2013年492例甲状腺手术切除标本进行回顾性分析。结果甲状腺微小癌119例,其中乳头状癌105例,滤泡癌11例,髓样癌3例,女性98例,占82.36%;男性21例,占17.64%。年龄14-80岁,平均年龄45.61岁。119例甲状腺微小癌中发生在单侧的104例,双侧15例,伴有周围淋巴结转移的15例。结论甲状腺微小癌女性发病占优势,肿瘤体积小、隐匿,诊断应结合组织结构及细胞学形态等综合特征,肿瘤分化较好,恶性程度相对较低,预后较其它肿瘤好。
Objective To investigate the clinicopathological features of thyroid microcarcinoma. Methods 492 cases of thyroidectomy from 2007 to 2013 in Department of Pathology, Peking University People’s Hospital were retrospectively analyzed. Results 119 cases of thyroid microcarcinoma, of which 105 cases of papillary carcinoma, follicular carcinoma in 11 cases, medullary carcinoma in 3 cases, 98 cases of women, accounting for 82.36%; male 21 cases, accounting for 17.64%. Age 14-80 years old, average age 45.61 years old. 119 cases of thyroid microcarcinoma occurred in unilateral 104 cases, bilateral in 15 cases, accompanied by peripheral lymph node metastasis in 15 cases. Conclusion The incidence of thyroid microcarcinoma is predominant in women. The tumor volume is small and concealed. The diagnosis should be combined with the characteristics of tissue structure and cytology. The tumor differentiation is good, the malignancy is relatively low, and the prognosis is better than other tumors.