最近我校传研室徐兆骥等的临床研究已充分证明槟榔制剂配合呋喃丙胺对血吸虫病患者有着良好疗效。槟榔对寄生于动物体内的血吸虫有促肝移作用。但当时用于试验的皆属槟榔的粗制剂,并不能说明槟榔中与呋喃丙胺发挥协同作用的为何种成分。纯粹的槟榔碱可使血吸虫的吸盘与体肌麻痹,过去虽有报道。但他们的观察是槟榔碱对在体外培养条件下曼氏血吸虫的作用,也不足以说明对寄生于动物体内日本血吸虫发挥作用的成份就是槟榔碱。因而我们进行了纯氢溴酸槟榔碱对小白鼠体内血吸虫促肝移作用的观察。 Recently, Xu Zhaji and other clinical research laboratories in our school have fully proved that betel nut preparations with furosemide have a good effect on schistosomiasis patients. Areca nut parasites in animals with schistosomiasis and promote hepatic function. However, the crude preparations of betel nut that were used for the test at that time did not explain what kind of ingredients are in the areca nut synergistically with furopyramine. Pure arecoline can make schistosome sucker and body muscle paralysis, although in the past have been reported. However, their observations were that the arecoline had an effect on Schistosoma mansoni under in vitro culture conditions and not enough to show that arecoline was the component that played a role in the schistosoma japonicum parasitic in animals. Thus, we performed arecoline hydrobromide on mouse liver schistosomiasis to promote the role of the observation.