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本文研究了外源性雌激素过多和内源性雌激素不足对小鼠移植性肿瘤 S_(180)的生长和免疫功能的影响。结果表明,注射外源性雌激素的小鼠肿瘤生长较快,胸腺显著萎缩,反映 T淋巴细胞的 ANAE(+)细胞百分数明显减少;摘除卵巢的小鼠与相应对照比,上述指标无显著差异。
This article investigated the effects of exogenous estrogen excess and endogenous estrogen deficiency on the growth and immune function of transplanted tumor S 180 in mice. The results showed that the mice injected with exogenous estrogen grew faster and the thymus significantly atrophied, reflecting a significant decrease in the percentage of ANAE(+) cells in T lymphocytes; there was no significant difference in the above indexes between the mice with ovariectomized and the corresponding controls. .