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口腔速崩片(rapidly disintegrating oral tablets,RDT)研制始于上世纪70年代,是近年来国内外市场上出现的一种新型口服速释固体制剂,是指可在无水或少量水存在下于口腔中快速崩解或溶解,随吞咽动作进入消化道的片剂[1]。该类片剂在口腔内遇到唾液后在几十秒内快速溶解,或在口腔内快速崩解,患者不需要水即可将药物顺利服下。此新剂型最适于儿童、老年、卧
Rapid development of oral disintegrating oral tablets (RDT) began in the 70s of last century, is a new type of oral immediate-release solid preparations appeared in domestic and foreign markets in recent years, refers to the water can be in the presence of water or a small amount of water in Rapid disintegration or dissolution in the mouth, with swallowing action into the digestive tract tablets [1]. Such tablets quickly dissolve within dozens of seconds after encountering saliva in the mouth or rapidly disintegrate in the oral cavity, and the patient can smoothly take the medication without water. This new formulation is best for children, the elderly, lying