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本文总结了西德二城市408例可评价的复发性和转移性乳腺癌放化疗结合同步治疗的临床经验。汉诺威市复发或转移性360例,纽伦堡市局部区域性复发48例。化疗应用CMF(V)(P)方案(环磷酰胺、氯甲喋呤、氟脲嘧啶、长春新碱、强的松)2周,重复使用多个周期(直到6周期)。在每个化疗周期中,对各肿瘤部位同时加放疗4～6次,分次剂量为2～3Gy。在各个化疗周期间隙及化疗最后2～3周内严格不用放疗。肿瘤放疗剂量为每个化疗周期10
This article summarizes the clinical experience of 408 concurrent evaluations of recurrent and metastatic breast cancer combined with concurrent therapy in two cities in West Germany. There were 360 cases of recurrence or metastasis in Hanover, and 48 cases of local recurrence in Nuremberg. Chemotherapy uses the CMF(V)(P) regimen (cyclophosphamide, chloromethyl purine, fluorouracil, vincristine, prednisone) for 2 weeks and multiple cycles (up to 6 cycles) are repeated. In each chemotherapy cycle, radiotherapy was simultaneously performed 4 to 6 times for each tumor site, and the divided dose was 2 to 3 Gy. Strictly do not use radiotherapy in the interval of each chemotherapy cycle and the last 2 to 3 weeks of chemotherapy. The dose of tumor radiotherapy is 10 for each chemotherapy cycle