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日本癌研中心收治原发性眼睑癌30例,男性12例,女性18例。年龄42~82岁。鳞癌21例,基底细胞癌6例,腺癌3例。肿瘤小于2cm者25例,2~5cm4例,5cm以上1例。开始使用软X线(40kV,滤过板Al1mm,SSD1cm),深X线160~250kV,滤过板Cu0.5mm。后改为高能X线(4、10MV)及β线(8、10MeV)。组织内~(252)cf照射。治疗后随访2个月~15年。作者见到,首次治疗的病例,鳞癌有3例(23%)局部复发,5例(38%)有淋巴结转移。基底细胞癌1例因糖尿病恶化,仅放疗9Gy而中断。其他医院治疗后复发的病例,鳞癌2例局部复发,5例淋巴结转移,且3例有远位转移。原发肿瘤不到2cm者17例,4例(20%)有局部复发及淋巴结转移。其他医院治疗后复发病例,不到2cm者8例,再放疗均未复发,但2~5cm的2例都复发。观察2年以上的鳞癌14例,13例照射野直径在3cm以上,2例复发;1例照射野直径在3cm以下,局部复发。总剂量
At the Japan Cancer Research Center, 30 cases of primary orbital cancer were treated, including 12 males and 18 females. Age 42 to 82 years old. There were 21 cases of squamous cell carcinoma, 6 cases of basal cell carcinoma, and 3 cases of adenocarcinoma. The tumors were less than 2cm in 25 cases, 2 to 5cm in 4 cases, and 5cm in 1 case. We started using soft X-rays (40kV, filter plate Al1mm, SSD1cm), deep X-rays 160 to 250kV, and filter plates Cu0.5mm. Later changed to high-energy X-ray (4, 10MV) and β-ray (8, 10MeV). Intra-tissue ~(252)cf irradiation. Follow-up from 2 months to 15 years after treatment. The authors saw that in the first case of treatment, there were 3 (23%) local recurrences of squamous cell carcinoma and 5 (38%) lymph node metastases. One case of basal cell carcinoma was aggravated by diabetes and was interrupted only by 9 Gy of radiotherapy. After retreatment in other hospitals, squamous cell carcinoma had local recurrence in 2 cases, lymph node metastasis in 5 cases, and distant metastasis in 3 cases. The primary tumor was less than 2cm in 17 cases, 4 cases (20%) had local recurrence and lymph node metastasis. After retreatment in other hospitals, 8 cases were less than 2cm, and no recurrence occurred after re-radiotherapy. However, 2 to 5cm of 2 cases all relapsed. Observed 14 cases of squamous cell carcinoma more than 2 years, 13 cases of radiation field diameter of more than 3cm, 2 cases of recurrence; 1 case of radiation field diameter below 3cm, local recurrence. Total dose