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氟脲嘧啶能诱发孕鼠骨髓和胎肝血嗜多染红细胞微核率的增高,与对照组比较有显著差异。胎肝血细胞对氟脲嘧啶的敏感性高于母鼠骨髓细胞。
Fluorouracil can induce the increase of the micronucleus rate of polychromatic RBCs in bone marrow and fetal liver of pregnant mice, which is significantly different from the control group. Fetal liver blood cells are more sensitive to fluorouracil than maternal bone marrow cells.