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地方性氟骨症(下简称氟骨症)在我国广泛流行,目前国内对本病的治疗方法不一,例如蛇纹石多含有致癌物石棉,钙剂加维生素D 不适用于硬化型氟骨症,高铝剂影响体内钙磷代谢,有导致软骨病的危险。因此,国内外都在探索和研究理想的治疗药物。1985年我们用复方硼砂片治疗31例氟骨症,初见疗效且无不良反应。为了探索复方硼砂片治疗氟骨症的疗效,1986年7月至1987年1月又观察了106例氟骨症,并进行动物实验。研究结果证明复方硼砂片疗效明显,报道如下:资料和方法一、流行区一般情况:研究对象河北省阳原县东井集居民,此地处在冀西北山间盆地,属于干旱富氟地区。原饮水含氟量3.1～8,1ppm,1984年改饮3.0～3.2ppm 新水源。全村氟斑牙患病率88%,
Local fluorosis (fluorosis) is widely prevalent in our country. At present, there are different treatment methods for this disease in our country. For example, serpentine contains carcinogenic asbestos. Calcium and vitamin D are not suitable for sclerosing fluorosis Symptoms, high-aluminum agents affect the metabolism of calcium and phosphorus, there is the risk of causing cartilage disease. Therefore, both at home and abroad are exploring and researching ideal therapeutic drugs. In 1985, we treated 31 cases of boricosis with compound borax tablets, with initial efficacy and no adverse reactions. In order to explore the efficacy of compound borax tablets in the treatment of skeletal fluorosis, another 106 skeletal fluorosis cases were observed from July 1986 to January 1987 and animal experiments were conducted. The results of the study show that the compound borax tablets have obvious curative effect and are reported as follows: Materials and Methods I. General Situation of Epidemic Area: The study population was residents of Dongjingji, Yangyuan County, Hebei Province. This locality is located in the mountainous basin of northwestern Hebei Province and belongs to arid and fluoride-rich areas. The original drinking water fluoride content of 3.1 ~ 8,1ppm, 1984 to drink 3.0 ~ 3.2ppm new water source. The prevalence of dental fluorosis 88% of the village,