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目的:评价用血必净注射液治疗中、重度烧伤患者的安全性和有效性。方法:将48例中、重度烧伤患者随机分为治疗组和对照组(每组24例);2组均给予常规治疗,而治疗组在常规治疗基础上加用血必净注射液;分析2组患者的体温、心率、血白细胞计数(WBC)、中性粒细胞计数、肝功能指标(AST,ALT)和肾功能指标(BUN,Cr)值的变化,以及抗菌药物的使用情况。结果:与对照组相比,治疗组能显著降低其体温、心率、血白细胞计数和中性粒细胞计数指标值,2组经统计学分析,其差异有统计学意义(P<0.05);肝、肾功能的有关指标值经统计学分析,其差异无统计学意义(P>0.05)。结论:血必净注射液用于治疗中、重度烧伤的疗效确切,且ADR少,临床值得推广应用。
Objective: To evaluate the safety and effectiveness of Xuebijing injection in the treatment of moderate and severe burn patients. Methods: Forty-eight patients with moderate-severe burns were randomly divided into treatment group and control group (24 cases in each group). The two groups were given routine treatment, while the treatment group was given Xuebijing Injection on the basis of conventional treatment. The changes of body temperature, heart rate, white blood cell count (WBC), neutrophil count, liver function index (AST, ALT) and renal function index (BUN, Cr) and the use of antibacterials were analyzed. Results: Compared with the control group, the treatment group can significantly reduce the body temperature, heart rate, white blood cell count and neutrophil count index values, the two groups by statistical analysis, the difference was statistically significant (P <0.05); liver The related index of renal function was statistically analyzed, the difference was not statistically significant (P> 0.05). Conclusion: Xuebijing injection for the treatment of moderate and severe burns curative effect is accurate, and less ADR, clinical worthy of promotion and application.