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探讨眼附属器淋巴组织增生性病变的增殖活性与组织学分型的关系。材料与方法:应用抗增殖细胞核抗原的单克隆抗体PC10和AgNORs技术对34例眼附属器淋巴组织增生性病变(包括良性淋巴组织增生14例,不典型增生9例,恶性淋巴瘤11例)的石蜡切片进行检测。结果:良性淋巴组织增生与后二者PCNA及AgNORs计数之间均有非常显著的差异(PCNAP<O.001AgNORsP<O.01及P<O.001),不典型增生与恶性淋巴瘤之间PCNA计数相差非常显著(P<0.01),AgNORS颗粒数量则无显著差异(P>0.05),同时发现AgNoRS与PCNA计数有良好的相关关系。结论二种技术对眼附属器淋巴组织增生性病变组织学分型有一定意义。
To investigate the relationship between the proliferative activity and histological types of lymphoid hyperplasia of the ocular adnexal apparatus. Materials and Methods: Anti-proliferating cell nuclear antigen monoclonal antibodies PC10 and AgNORs were used in 34 cases of ocular adnexal lymphoproliferative diseases (including benign lymphoproliferation in 14 cases, atypical hyperplasia in 9 cases, malignant lymphoma in 11 cases). Paraffin sections were examined. RESULTS: There was a significant difference between benign lymphoproliferative tissue and the latter two counts of PCNA and AgNORs (PCNAP0.05). At the same time, it was found that there was a good correlation between AgNoRS and PCNA counts. Conclusion The two techniques have a certain significance for the histological classification of ocular adnexal lymphoproliferative lesions.