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目的探讨类风湿关节炎(RA)相关实验指标的临床诊断性能及诊断效果。方法 90例类风湿关节炎患者作为实验组,同期90例健康体检者作为对照组。采用电化学发光法定量测定两组抗环瓜氨酸抗体(anti-CCP),采用免疫速率散射比浊法定量测定类风湿因子(RF)、C反应蛋白(CRP),采用仪器法检测红细胞沉降率(SR),分析类风湿关节炎相关实验指标诊断性能。结果两组研究对象CRP以及SR指标比较,差异无统计学意义(P>0.05);实验组诊断后anti-CCP、RF指标显著高于对照组,差异有统计学意义(P<0.05)。结论类风湿关节炎患者采用anti-CCP、RF、CRP以及SR效果理想,能够为患者临床诊断、治疗提供参考,值得推广应用。
Objective To investigate the clinical diagnostic performance and diagnostic efficacy of rheumatoid arthritis (RA) related experimental indexes. Methods Ninety patients with rheumatoid arthritis were selected as experimental group and 90 healthy subjects as control group. The levels of anti-cyclic citrullinated antibody (anti-CCP) were measured by electrochemiluminescence immunoassay. The levels of rheumatoid factor (RF) and C-reactive protein (CRP) were measured by the immunostaining nephelometry. Rate (SR), analysis of rheumatoid arthritis related experimental indicators diagnostic performance. Results There was no significant difference in CRP and SR between the two groups (P> 0.05). The levels of anti-CCP and RF in the experimental group were significantly higher than those in the control group (P <0.05). Conclusion The results of anti-CCP, RF, CRP and SR in patients with rheumatoid arthritis are satisfactory, which can provide reference for the clinical diagnosis and treatment of patients, which is worth popularizing and applying.