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本文报道豚鼠在噪声暴露前后吸2atm或latm纯氧对噪声性听觉损伤的影响。暴露噪声是1/3oct窄带噪声,中心频率1000Hz,强度136dB作用1h。在噪声暴露前或暴露后吸2atm纯氧可以减小噪声引起的永久性听阈偏移(对短声)。吸2atm纯氧所起的作用(预防吸氧一次或治疗吸氧六次,每次1h),相当于把噪声强度降低1OdB(从136dB降至126dB。预防吸氧(暴露前吸氧)比治疗吸氧(暴露后吸氧)效果好。吸2atm纯氧比latm有效。文中讨论了吸高压氧或高浓度氧在预防和治疗噪声性听觉损伤中的某些机理。
This article reports the guinea pig noise exposure before and after 2atm or latm pure oxygen noise auditory damage. Exposure noise is 1 / 3oct narrowband noise, the center frequency of 1000Hz, the intensity of 136dB role 1h. Suction of 2 atm pure oxygen before or after noise exposure can reduce permanent noise threshold shifts (for short sounds). The effect of inhaling 2 atm of pure oxygen (preventing oxygen inhalation or treating oxygen six times for 1 h each) is equivalent to reducing the noise level by 1 dB (from 136 dB to 126 dB). Prevention of oxygen inhalation (pre-exposure oxygen) Oxygen absorption (post-exposure oxygen) is effective, and 2 atm pure oxygen is more effective than latm. Some mechanisms for hyperbaric or hyperbaric oxygen exposure to prevent and treat noise-induced hearing impairment are discussed.