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目的 探讨乳腺对维生素E（VE）的分泌能力。方法 将78例健康孕妇随机分为三组，围生期VE补充组口服两种剂量的VE，对照组为同期孕产妇。产后d3采集母乳，高效液相色谱法测定母乳VE浓度。结果 1.VE补充组妇女母乳VE浓度明显高于对照组（P＜0.01);2.每天口服50 mg VE者较每天口服100 mg VE的妇女相比，母乳VE水平无显著差异（P＞0.05）。结论 人乳腺具有较强的VE分泌能力，维持围生期孕妇良好的VE营养水平，对改善新生儿VE 营养状况有积极意义。
Objective To investigate the secretion of vitamin E (VE) in breast. Methods Seventy eight healthy pregnant women were randomly divided into three groups. Peripheral VE supplementation group received two doses of VE. The control group was pregnant women of the same period. Breast milk was collected at postnatal day 3 and the concentration of VE in breast milk was determined by high performance liquid chromatography. Results 1. The VE concentration of breast milk in the vitamin E supplementation group was significantly higher than that in the control group (P <0.01). 2. There was no significant difference in the VE level of the breast milk among the women taking orally 50 mg VE daily compared with those taking orally 100 mg VE daily (P> 0.05 ). Conclusion The human mammary gland has strong VE secretion capacity and maintain the good VE nutrition level of perinatal pregnant women, which has a positive meaning to improve the nutritional status of neonatal VE.