论文部分内容阅读
为探讨急进高原环境人群，早期适应过程中红细胞抗氧化指标—谷胱甘肽（ＧＳＨ）、谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）和超氧歧化酶（ＳＯＤ）的变化及其生理意义。以急进高原的健康人群为研究对象，年龄１８～２１岁。分为对照组和高原低氧组进行研究。结果表明高原低氧组红细胞ＧＳＨ含量和ＧＳＨ－Ｐｘ活力显著低于对照组（Ｐ＜０．０５）。高原低氧组红细胞ＳＯＤ含量显著高于对照组（Ｐ＜０．０５）。说明人体急进高原后血红细胞中抗氧化系统发生一系列适应性反应，但在低氧适应过程中的生理作用仍需进一步探讨。
In order to investigate the changes of erythrocyte antioxidant indexes, glutathione (GSH), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD), and their physiological significance. The rapid population of healthy people as the research object, aged 18 to 21 years old. Divided into control group and plateau hypoxia group to study. The results showed that GSH content and GSH-Px activity of erythrocytes in plateau hypoxia group were significantly lower than those in control group (P <0.05). Plateau hypoxia group erythrocyte SOD content was significantly higher than the control group (P <0.05). It shows that a series of adaptive reactions occur in the antioxidant system of red blood cells after the human body reaches the plateau rapidly. However, the physiological role in the process of hypoxia adaptation still needs to be further explored.