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目的探讨影响肝硬化自发性细菌性腹膜炎(SBP)患者预后的相关因素。方法将130列肝硬化SBP患者分为治愈好转组和无效死亡组,分析比较2组患者临床资料,并对有意义的单因素进一步行Logistic回归分析。结果单因素分析显示SBP病史、上消化道出血、肝性脑病、肝肾综合征、休克血压、重度低钠血症、高胆红素血症和脉博>100次/min8个因素在2组间的差异有显著性(P均<0.05);而年龄、性别、肝硬化原因、血清白蛋白、腹水总蛋白、腹水白细胞、凝血酶原时间和是否合并糖尿病等因素的差异无显著性(P均>0.05)。Logistic回归分析表明:SBP病史、肝肾综合征、休克血压和脉博>100次/min是影响肝硬化SBP预后的独立危险因素。结论SBP病史、肝肾综合征、休克血压和脉博>100次/min4个因素可能是影响肝硬化SBP预后的独立高危因素,对于具有这些高危因素的患者在临床中应加以重视。
Objective To investigate the prognostic factors of patients with spontaneous bacterial peritonitis (SBP) in cirrhosis. Methods 130 patients with cirrhosis SBP were divided into two groups: the cured improvement group and the ineffective death group. The clinical data of the two groups were compared and analyzed. Logistic regression was used to analyze the single significant factors. Results Univariate analysis showed that SBP history, upper gastrointestinal bleeding, hepatic encephalopathy, hepatorenal syndrome, shock blood pressure, severe hyponatremia, hyperbilirubinemia and pulse rate> 100 beats / min were significantly different in group 2 (P <0.05). There was no significant difference in age, sex, cirrhosis, serum albumin, total protein in ascites, ascites leukocyte, prothrombin time and whether or not diabetes mellitus (P All> 0.05). Logistic regression analysis showed that the SBP history, hepatorenal syndrome, shock blood pressure and pulse rate> 100 beats / min were independent risk factors for the prognosis of cirrhotic patients with SBP. Conclusion SBP history, hepatorenal syndrome, shock blood pressure and pulse rate> 100 beats / min may be independent risk factors for the prognosis of cirrhotic patients with SBP. Patients with these high risk factors should be emphasized clinically.