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目的 回顾性分析977例超声引导下经皮肺外周型病变穿刺活检确诊率和并发症发生的影响因素,从而提高确诊率和降低并发症发生率.方法 采用多因素Logistic回归分析评估多个变量因素,如患者年龄、性别、病变大小、位置、穿刺针内径、穿刺次数等对穿刺确诊率及并发症发生率的影响.结果 病变最大径≤2 cm (P＜0.001)和病变位于肺下叶(P=0.011)是确诊率的重要影响因素.穿刺次数≥3次(P=0.001)是并发症发生的高危因素.结论 超声引导下肺穿刺活检是诊断肺部外周病变的高效且安全的检查方法,掌握适应证并熟练穿刺技巧可提高穿刺确诊率和降低并发症发生率.“,”Objective To retrospectively analyze the influencing factors of 977 cases of the diagnosis rate and complication of percutaneous biopsy of pulmonary peripheral lesions under ultrasound guidance,so as to improve the diagnosis rate and reduce the incidence of complications.Methods Multivariate logistic regression analysis was used to assess diagnosis rate and complication rate influenced by multiple variables including age,sex,lesion size,location,puncture needle diameter,puncture frequency,etc.Results The maximal diameter of the lesion less than 2 cm (P＜0.001) and the lesion located in the lower lobe (P=0.011) were both important influence factors for pathological diagnosis.The number of puncture times ≥3 (P=0.001) was an risk factor for the occurrence of complications.Conclusions Lung biopsy under ultrasound guidance is an effective and safe method for the diagnosis of pulmonary peripheral lesions.Mastering the indications and skilling puncture skills can improve of diagnosis rate and reduce the incidence of complications.