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对１４例病理诊断为急性肾间质小管性疾病的肾活检组织标本采用免疫组化法对肾间质细胞浸润进行了研究。结果显示：急性肾间质小管性疾病病因可多种多样，损害程度为可逆性和不可逆性；肾间质中浸润的炎性细胞主要为ＣＤ６８和ＣＤ４５ＲＯ阳性细胞，也可见ＣＤ２０阳性细胞。表明浸润的巨噬细胞以及Ｔ淋巴细胞可能在急性肾间质小管性疾病进展过程中起重要作用。
The renal interstitial cell infiltration of 14 cases of pathologically diagnosed renal interstitial tubulointerstitial lesions was studied by immunohistochemistry. The results showed that the causes of acute tubulointerstitial tubulointerstitial disease may be varied and the degree of damage is reversible and irreversible. The infiltrating inflammatory cells in the renal interstitium are mainly CD68 and CD45RO positive cells and CD20 positive cells. It indicates that infiltrating macrophages and T lymphocytes may play an important role in the progression of acute tubulointerstitial disease.